Lipid Profile in PTS of Type 02 Diabetes Mellitus with & without Hypertension

Abstract

Introduction: Diabetes causes hyperglycemia, glucose, lipid, and protein metabolic issues owing to insufficient insulin production or activity resulting in dyslipidemia and hypertension. Dyslipidemia raises triglycerides, free fatty acids, and serum HDL cholesterol, causing cardiovascular events including high blood pressure.
Objective: The current study aimed to evaluate the serum lipid profiles of type 02 diabetics with and without hypertension. Study layout The research strategy is experimental, using a comparative study method.
Methodology: Mercy Teaching Hospital and Prime Hospital, Peshawar, performed the study. 6-month research. Peshawar's Prime and Mercy Teaching Hospitals conducted lab tests from July to December 2021. Descriptive-analytic research was our objective. Cases and controls were chosen among 200 type 02 diabetics. Cases comprised type 02 diabetics with hypertension; controls had none. Blood cholesterol, triglyceride, LDL, and HDL were measured. Statisticians utilised SPSS 24. Comparing groups' means using a student T-test.
Result: Patients averaged 51.33 6.35 years old. Our patients were mostly 41-50. 82 (41%) men and 112 (59%) women participated in our research. Mean blood cholesterol, triglycerides, and low-density lipoprotein (LDL) values in cases and controls were 211.40 101.64 mg/dL vs 158.88 31.84 mg/dL, 307.95 167.17 mg/dL vs 154.39 59.12 mg/dL, and 115.57 82.26 mg/dL vs 94.40 Serum cholesterol, triglyceride, and LDL values were significant (p0.01).
Serum HDL in controls (44.23 6.41mg/dL) was greater than in controls (41.13 4.96mg/dL) but not statistically significant (p-value > 0.05).
Conclusion: Our study found that hyperlipidemia is common in type 2 diabetes mellitus patients with hypertension, However the mechanism of this connection is uncertain.
Keywords: Diabetes mellitus type 2 , Dyslipidemia, hypertension, Peshawar, Pakistan