Biochemical and Histophysiological impact of Curcumin on Breast Cancer. A Cross Sectional Clinical Study

Authors

  • Naveed Shuja, Uzma Hameed, Hasan Akbar Khan, Allah Wadhayo Kalo, Urwa Sarwar, Muhammad Waqas Khan

DOI:

https://doi.org/10.53350/pjmhs22163462

Keywords:

Curcuma longa, Breast cancer, Carcinoembryonic antigen, Tumor markers, Curcumin

Abstract

Hypothesis: The active anti-carcinogenic compound of Curcuma longa a member of ginger family is curcumin which inhabit the growth of tumor in breast cancer. 

Aims and objectives: The aims and objectives of present study were to determine the clinical and preclinical effects of   curcumin against breast cancer.  

Materials and Methods: 100 women patients with grade- I and grade-II breast cancer were treated with 10g/day curcumin powder orally for six months. The tumor markers such as CA 15-3, CA 27.29, Carcinoembryonic antigen (CEA) and CA 125 were measured from blood serum of each patient.

Conclusion: In the present study it was concluded that a significant changes (p<0.05) come out after 6 month in blood serum levels of 10mg/day oral curcumin treated group-B and group–D as compared to group-A and group-C regarding tumor markers such as CA 15-3, CA 27.29, Carcinoembryonic antigen (CEA) and CA 125.

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How to Cite

Naveed Shuja, Uzma Hameed, Hasan Akbar Khan, Allah Wadhayo Kalo, Urwa Sarwar, Muhammad Waqas Khan. (2022). Biochemical and Histophysiological impact of Curcumin on Breast Cancer. A Cross Sectional Clinical Study. Pakistan Journal of Medical & Health Sciences, 16(03), 462. https://doi.org/10.53350/pjmhs22163462

Issue

Vol. 16 No. 03 (2022): Pakistan Journal of Medical & Health Sciences

Section

Articles

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