Efficacy of Intravenous Dexamethasone and Placebo in Postop Sore Throat Prevention after Oral Endotracheal Intubation

Authors

  • Mahendar, Udesh Kumar, Kainat, Ravi Kumar, Rajesh, Ajeet Kumar

DOI:

https://doi.org/10.53350/pjmhs2023174120

Abstract

Aim: To compare the efficacy of intravenous dexamethasone with placebo in preventing POST after endotracheal intubation in general surgical patients.
Design: Randomized controlled trial.
Place and duration of study: Department of Anesthesiology and Surgical Intensive Care Unit and Pain Management, Civil Hospital, Dow University of Health Sciences Karachi from 12th January 2015 to 11th July 2015.
Methodology: Sixty six patients underwent elective surgical procedures with tracheal intubation were included. Patients were randomly divided in Group A treated with dexamethasone and Group B treated with normal saline. Anesthesia was induced 5 minutes later. Tracheal intubation was performed after ensuring maximum neuromuscular blocking affect. At the end of the 24 hours after surgery POST was evaluated by VAS.
Results: Thirty seven (56.1%) were males and 29(43.9%) were females. Efficacy was significantly high in group A as compare to group B (84.4% vs. 33.3%; p=0.0005].
Conclusion: Prophylactic intravenous administration of dexamethasone was associated with a statistically significant reduction in the incidence of POST after tracheal extubation.
Keywords: Sore throat, Dexamethasone, Endotracheal intubation, General surgical

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How to Cite

Mahendar, Udesh Kumar, Kainat, Ravi Kumar, Rajesh, Ajeet Kumar. (2023). Efficacy of Intravenous Dexamethasone and Placebo in Postop Sore Throat Prevention after Oral Endotracheal Intubation. Pakistan Journal of Medical & Health Sciences, 17(04), 120. https://doi.org/10.53350/pjmhs2023174120

Issue

Vol. 17 No. 04 (2023): Pakistan Journal of Medical & Health Sciences

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Articles

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