Evaluation of Absolute Neutrophil Count, Band Count and Morphological Changes in Neutrophils in Bacterial Infections

Authors

  • Saadia Latif, Hamid Iqbal, Jawad Zafar, Tamoor Chughtai, Saadat Parveen, Aayza Mujahid

DOI:

https://doi.org/10.53350/pjmhs202317436

Abstract

Aim: To evaluate the absolute neutrophil count, band count and morphological changes in diagnosing acute bacterial infections among patients presenting with acute febrile illness.

Methodology: It was cross sectional analytical study conducted after taking approval from institutional ethical review committee. Total 726 patients were included. The cut-off for leukocytosis was 19.6x109/l. Counted 200 WBC.  Band cells were counted according to College of American Pathologists Survey criteria. If band count is 20%, it is considered an increased count. Chi square test was applied.

Results: The Acute neutrophil count was elevated significantly in positive cases (p<0.01). Band cells were elevated in +ve cases when comparing with their counterpart (p<0.01). The morphological changes in neutrophils in both culture positive and negative samples showed that toxic granules were seen in > ¾ samples, Dohle bodies in 80.9% and vacuoles in 69.1% culture positive cases.

Conclusion: Study findings indicate that ANC and band count is significantly higher in patients with acute bacterial infection.

Keywords: Neutrophil, Toxic granulation, Bacterial infections

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How to Cite

Saadia Latif, Hamid Iqbal, Jawad Zafar, Tamoor Chughtai, Saadat Parveen, Aayza Mujahid. (2023). Evaluation of Absolute Neutrophil Count, Band Count and Morphological Changes in Neutrophils in Bacterial Infections. Pakistan Journal of Medical & Health Sciences, 17(04), 36. https://doi.org/10.53350/pjmhs202317436

Issue

Vol. 17 No. 04 (2023): Pakistan Journal of Medical & Health Sciences

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Articles

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