Megrment the Level of SDF1-Α in the Serum of Patients with Urinary Tract Infection and Patients with Vaginal Infection

Abstract

Urinary tract infection, Bacterial vaginosis as one of the global threats affecting millions of women and causing some time deaths around the world.

Objective: This study aims to assess levels of SDF1 and IgA in patients with Urinary tract infection, Bacterial vaginosis, and people enjoying good health as a control group.

Methods: Collecting medical information from (180) participants in the Imam Al-Sadiq General Teaching Hospital in Iraq-Babylon, the Gynecology Consultant, according to specific criteria, the subjects were divided into three groups: the control group, the patients (UTI, BV), while the demographic study included age, education, Jobs, and living Laboratory results, signs and symptoms, SDF1-α and IgA levels were assessed by the enzyme-linked immunosorbent assay (ELISA) technique.

Results: The results revealed that there were significant variations in SDF1 and IgA between the UTI group, BV group, and control groups. SDF1 level with the UTI group was (1.206522 ±.0927277 pg/ml) and for patients with BV  was(1.213735 ±.0661389 pg/ml) whereas the control group appear was (1.130013±.0496400 pg/ml), IgA level in the UTI patients was (64.252983 ± 7.5946759pg/ml) and patients with BV was (60.441928±6.1457661pg/ml) whereas the control group appears was  (48.011745 ±4.7938613 pg/ml)

Conclusion: They can be considered good indicators to give knowledge about the diagnosis of urinary tract infection and bacterial vaginosis, and help doctors to give appropriate medications.

Keywords: Urinary tract infection, bacterial vaginosis, stromal cell-derived factor 1-alpha, Immunoglobulin A.