Frequency of Left Ventricular Mechanical Dyssynchrony in Chronic Heart Failure

Abstract

Objective: To determine the frequency of left ventricular mechanical dyssynchrony in chronic heart failure patients.

Material and Methods: After approval from the Hospital ethical committee, the study was conducted in the department of cardiology Hayatabad medical complex Peshawar from 1^st September  2021 to 28^th February  2022.  In this descriptive cross-sectional study, 155 patients in total were examined while 27% of heart failure patients had mechanical dyssynchrony, a 95% confidence interval, and a 7% margin of error were maintained according to WHO sample size computations.

Results: This study's participants had an average age of 60, with a standard deviation of ±1.26 years. 62% of the patients were male, compared to 38% of females. 35% of patients had a Broad QRS complex, whereas 65% of patients had a Narrow QRS complex. Mechanical dyssynchrony was identified in 32% of chronic heart failure patients.

Conclusion: Patients in chronic heart failure with QRS > 150ms and having mechanical dyssynchrony are benefited with Cardiac Ressynchronisation Therapy (CRT) implantation which reduces morbidity and mortality, while those with a narrow QRS (<150ms) are generally non – responders.

Keywords: Mechanical dyssynchrony, chronic heart failure,  left ventricular ejection fraction