Frequency of Congenital Hypothyroidism in Newborn at Tertiary Care Hospital in Quetta

Authors

  • Abdul Baqi Essazai, Zakaullah Kakar, Syed Moeed Ahmed, Naseeb Ullah, Pir Jan, Najeebullah

DOI:

https://doi.org/10.53350/pjmhs20221612242

Abstract

Objective: To determine the frequency of congenital hypothyroidism (CH) in newborn at tertiary care hospital in Quetta, Pakistan.

Study design: Cross-sectional study.

Place and Duration: The Department of Paediatrics, Unit-II, Bolan Medical College Hospital, Quetta, Pakistan from January 2022 to June 2022.

Methodology: Neonates of both genders born with birth weight above 1500 grams having gestational age above 28 weeks, presenting between 3 to 5 days following birth were analyzed. At the time of enrollment, demographic characteristics of the neonates were noted and screening of CH was done. The CH was labeled as serum TSH ≥ 20mU/ml and T4 < 9 pmol/l.

Results: During the study period, a total of 383 neonates as per inclusion/exclusion criteria were analyzed. There were 239 (62.4%) boys and 144 (37.6%) girls. The mean age was 3.87+0.843 days. The mean TSH level was 12.807+5.11 mU/ml (ranging 7 to 50 mU/ml). We noted that CH was found in 10 neonates (2.6%).

Practical Implications: The reported frequency of CH seems higher as compared to contemporary literature which raises the importance of CH screening programs at national level.

Conclusion: The frequency of congenital hypothyroidism was 2.6% among newborns at a tertiary care hospital of Quetta, Pakistan.

Keywords: Congenital hypothyroidism, newborn, thyroid-stimulating hormone

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How to Cite

Abdul Baqi Essazai, Zakaullah Kakar, Syed Moeed Ahmed, Naseeb Ullah, Pir Jan, Najeebullah. (2023). Frequency of Congenital Hypothyroidism in Newborn at Tertiary Care Hospital in Quetta. Pakistan Journal of Medical & Health Sciences, 16(12), 242. https://doi.org/10.53350/pjmhs20221612242