Histological Features and Predictors of Early Relapse in Patients of Ulcerative Colitis

Authors

  • Momina Jehangir Khan, Fariha Sehrish, Aman ur Rehman, Sahar Iqbal, Anam Ilyas, Rabia Mukhtar

DOI:

https://doi.org/10.53350/pjmhs22168229

Abstract

Objective: To determine the proportion of histological features and histological feature predicting frequency of elapse in known patients of ulcerative colitis.

Methodology: One hundred and ninety cases each had endoscopic colonic biopsies from the rectum, distal colon, and proximal colon.

Study Design: Retrospective Case series

Setting: Sheikh Zayed Hospital Lahore, Department of Histopathology, from February 25, 2016, to February 25, 2017.

Results: The majority of patients complained of generalized abdominal pain (55.3%). The commonest histological feature is cryptitis 189(99.5%). Majority patients with basal plasmacytosis 38(42.2%) and crypt abscess 36(29.8%) relapsed at 4th month.

Conclusion: Histological features basal plasmacytosis and crypt abscess are of prognostic importance. A greater chance of relapse can be predicted in patients with increased number of basal plasma cells and cryptitis. These findings will help in further management of ulcerative colitis patients.

Keywords: Inflammatory bowel disease, Ulcerative colitis, Remission, Relapse

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How to Cite

Momina Jehangir Khan, Fariha Sehrish, Aman ur Rehman, Sahar Iqbal, Anam Ilyas, Rabia Mukhtar. (2022). Histological Features and Predictors of Early Relapse in Patients of Ulcerative Colitis. Pakistan Journal of Medical & Health Sciences, 16(08), 229. https://doi.org/10.53350/pjmhs22168229

Issue

Vol. 16 No. 08 (2022): Pakistan Journal of Medical & Health Sciences

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Articles

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