Increased Chronic Urothelial Inflammation and its Association with Urinary Tract Infection

Authors

  • Tauheed Farid, Ibrahim Ahmad, Mati Ur Rehman, Farooq Malik, Safiullah Sohu, Qurat-Ul-Ain Iqbal

DOI:

https://doi.org/10.53350/pjmhs22165984

Abstract

Introduction: Inflammation of the bladder can be due to both noninfectious and infectious etiologies. The most common cause of infectious cystitis has been Escherichia coli.

Objectives: The basic aim of the study is to find the increased chronic urothelial inflammation and its association with urinary tract infection.

Material and methods: This cross sectional study was conducted in Ganga Ram hospital, Lahore during June 2020 to December 2020. The data was collected from 50 patients. Bladder symptoms and lower urinary tract conditions were investigated. All patients were treated actively according to the latest urine culture and followed by antimicrobial prophylaxis for at least 1 month.

Results: The data was collected from 50 patients. The mean age was 45± 3.56 years for male and 52.3 ± 8.89 years for females. The analysis of data shows the differences in urodynamic variables between the control subjects and the ESRD/CKD patients.

Conclusion: It is concluded from our study that increased urothelial inflammation and apoptosis and decreased cell expression were found in patients with ESRD/CKD. 

Downloads

How to Cite

Tauheed Farid, Ibrahim Ahmad, Mati Ur Rehman, Farooq Malik, Safiullah Sohu, Qurat-Ul-Ain Iqbal. (2022). Increased Chronic Urothelial Inflammation and its Association with Urinary Tract Infection. Pakistan Journal of Medical & Health Sciences, 16(05), 984. https://doi.org/10.53350/pjmhs22165984

Issue

Vol. 16 No. 05 (2022): Pakistan Journal of Medical & Health Sciences

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.