Comparison of Topical and Combined Treatment of Bacterial Vaginosis

Authors

  • Naila Khawer, Sadaf Kashif, Amna Asif, Shagufta Jabbar, Zille Huma, Fariha Arshad

DOI:

https://doi.org/10.53350/pjmhs22165333

Keywords:

Bacterial vaginosis, clindamycin, metronidazole, females, reproductive age

Abstract

Objective: To compare efficacy of topical clindamycin versus combined effect of metronidazole and clindamycin in bacterial vaginosis patients.

Study Type: Randomized controlled trial

Place and Duration of Study: Obstetrics and Gynecology Unit 3, Services hospital, Lahore from 25th January 2018 to 25th July 2018.

Methodology: Sixty patients fulfilled selection criteria were divided randomly in twp study groups. Clindamycin topical application was given to group A and second group was given clindamycin topical treatment plus oral metronidazole. Patients were called in OPD after 2 days and checked for bacterial vaginosis.

Results: The mean age was 30.35±7.65 years. Twelve (20%) females were nulliparous, 16 (26.7%) had parity 1, 16 (26.7%) had parity 2, 10 (16.7%) had parity 3 and 6 (10%) had parity 4. In clindamycin group, efficacy was achieved in 22 (73.3%) cases while 28 (93.3%) cases in combination group. The difference between both groups was significant (p<0.05).

Conclusion: The combination of clindamycin and metronidazole is more effective in resolution of bacterial vaginosis than clindamycin alone.

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How to Cite

Naila Khawer, Sadaf Kashif, Amna Asif, Shagufta Jabbar, Zille Huma, Fariha Arshad. (2022). Comparison of Topical and Combined Treatment of Bacterial Vaginosis. Pakistan Journal of Medical & Health Sciences, 16(05), 333. https://doi.org/10.53350/pjmhs22165333

Issue

Vol. 16 No. 05 (2022): Pakistan Journal of Medical & Health Sciences

Section

Articles

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